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Phcog.net publishes peer-reviewed journals covering the aspect inter-linked with natural product drug development and its associated fields. The journals aim to offer high-quality content which is scientifically sound, reviewed and established to leverage the natural drug development.
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Recently Published Article
- Two new xeniolide diterpenes from the soft coral Xenia umbellata; displayed anti proliferative effectsWalied M Alarif, Mohamed A Ghandourah, Ahmed Abdel Lateff, Nahed O Bawakid, Ahmed Abdullah Alotaibi, Mohammad Y Alfaifi, Serag Eldin I. ElbehairiPharmacognosy Magazine 2020 16(72):774-779 Background and Objective: Xenia is an octocoral genus of family Xeniidae. It contains 98 species and is rich of xenican-type diterpenoids. These compounds play an important role in the biological […]
- Terfezia claveryi and Terfezia boudieri extracts: An antimicrobial and molecular assay on clinical isolates associated with eye infectionsLorina Ineta Badger-Emeka, Promise Madu Emeka, Saif Aldossari, Hany Ezzat KhalilPharmacognosy Magazine 2020 16(72):780-788 Background: Ocular infections are capable of spreading to different anatomical sites of the eyes and, if not appropriately treated, can lead to blindness. The emergence of difficult to treat microbial infections has led to the search of alternatives from natural sources. […]
- Anti-inflammatory and anti-cell proliferative effects of dieckol in the prevention and treatment of colon cancer induced by 1,2-dimethyl hydrazine in experimental animalsBaoxiu Yang, Ying Li, Zhengbo Yang, Legang Xue, Minqin Zhang, Guoliang Chen, Arunachalam Chinnathambi, Tahani Awad Alahmadi, Xu LiuPharmacognosy Magazine 2020 16(72):851-858 Objectives: Colon carcinogenesis is a major cause of mortality and morbidity in developing and developed countries, and its etiology is familiar to be a grouping of environmental and nutritional factors, hereditary factors, and […]
- Anwulignan from the fruits of Schisandra chinensis and its cytotoxicity against human cancer cell linesPharmacognosy Magazine 2020 16(72):695-699 Background: The fruits of Schisandra chinensis have been used traditionally as the medicinal materials in East Asia. Their extracts have been reported to be cytotoxic to several cancer cells and phytochemical research has identified numerous cytotoxic lignans. Objectives: We reviewed for the effects of cytotoxic lignans against various human cancer cells. […]
- Synergistic and toxicity-attenuating effects of Periplaneta americana extract CII-3 combined with cisplatin on lewis lung cancer-bearing miceQiaoling Yang, Mili Shi, Guangming Liu, Fang Peng, Xiaobo Liu, Meixian GuoPharmacognosy Magazine 2020 16(72):817-829 Objective: The objective was to study the synergistic and attenuating effects of CII-3 combined with cisplatin. Materials and Methods: A Lewis tumor-bearing mouse model was established. After 15 days of continuous administration of CII-3 and cisplatin, the pathological changes in […]
- Inhibitory effects of triterpenoid betulin on inflammatory mediators inducible nitric oxide synthase, cyclooxygenase-2, tumor necrosis factor-alpha, interleukin-6, and proliferating cell nuclear antigen in 1,2-dimethylhydrazine-induced rat colon carcinogenesisJinfeng Yu, Min Li, Dong Zhan, Chang Shi, Le Fang, Chunmei Ban, Weifeng Zheng, Vishnu Priya Veeraraghavan, Surapaneni Krishna Mohan, Xiaoling TangPharmacognosy Magazine 2020 16(72):836-842 Background: Colon carcinogenesis is the third most commonly occurring malignant neoplasm and the second most common cause of cancer-related deaths globally. Betulin (BE) is a pentacyclic lupane-type triterpenoid naturally dispersed […]
- Astaxanthin attenuates contrast-induced acute kidney injury through silent mating-type information regulation 2 homolog-1/peroxisome proliferator-activated receptor γ co-activator–α/NRF1 signaling pathwayPharmacognosy Magazine 2020 16(72):733-737 Objectives: In this study, we established a model of contrast-induced acute kidney injury with iohexol. This model was used to investigate whether astaxanthin (AST) attenuates oxidative stress and apoptosis by activating silent mating-type information regulation 2 homolog-1 (SIRT1) signaling pathway in rat renal tubular epithelial cells (NRK-52E). Materials and Methods: NRK-52E […]
- Juglanin attenuated adjuvant-induced arthritis via inactivating NF-κB/IκBα and a disintegrin-like and metalloproteinase domain with thrombospondin-1 repeat pathways in experimental ratsChao Ning, Shaoqi Ning, Heng Luo, Lei YanPharmacognosy Magazine 2020 16(72):803-811 Background: Rheumatoid arthritis (RA) is an autoimmune and inflammatory disease affecting multiple joints and worsening the quality of life. Juglanin, a natural aldose reductase inhibitor, has shown to exhibit anti-inflammatory, anti-nociceptive, and anti-oxidant properties. Objective: The present study was undertaken to evaluate their possible […]
- Preclinical study on effects of Acalypha indica on streptozotocin-induced liver damage in diabetic ratsPharmacognosy Magazine 2020 16(72):722-729 Background: Diabetes is one of the most common non-communicable global diseases. It is the fourth leading cause of death, thus posing a serious threat to human beings. The conventional drugs developed along the principles of Western medicine are often limited in efficacy in diabetes management. However, significant evidences suggest that polyphenol-rich […]
- Neeraj Kumar Fuloria, Shivkanya Fuloria, Vijay Kumar Sharma, Mohammed Ali, Amit Singh, Pradeep Kumar SharmaPharmacognosy Magazine 2020 16(72):730-732 Background: Capsicum annuum (CA) fruits are consumed in the human diet for more than six centuries. Less research evidence for critical isolation experiment over CA fruits methanolic extract (CAFME) is an important concern for the investigators. Objectives: […]