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Phcog.net publishes peer-reviewed journals covering the aspect inter-linked with natural product drug development and its associated fields. The journals aim to offer high-quality content which is scientifically sound, reviewed and established to leverage the natural drug development.
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Recently Published Article
- Colocasia esculenta L. schott corm mucilage: A selective COX-2 inhibitor for treatment of irritable bowel syndromeNesrin M Fayek, Samar M Mouneir, Azza Ramy Abdel Monem, Samia M Abdelwahab, Nebal D EltanboulyPharmacognosy Magazine 2021 17(74):387-390 Background: Therapeutic strategies used for the treatment of irritable bowel syndrome having many limitations due to their side effects; this necessitates searching for new substitutes with similar therapeutic results and limited side effects. In the present […]
- Therapeutic targets and biological mechanisms of curcumol on atherosclerosis: A study based on network pharmacology approach and biological studiesBaolian Ma, Shilin Yang, Junmao Li, Zhiqi Wen, Hui Ouyang, Wugang Zhang, Yulin Feng, Mingzhen HePharmacognosy Magazine 2021 17(74):216-222 Background: Atherosclerosis is an extremely predominant condition. The morbidity and mortality of cardiovascular and cerebrovascular ailments caused by atherosclerosis have augmented significantly in recent years. The discovery and research of new drugs are therefore obligatory and […]
- Chemoprotective effect of crocetin against 1,2 dimethyl hydrazine induced colorectal cancer in albino wistar rats through antioxidant pathwayPeng Shao, Xiujuan Li, Xin GuanPharmacognosy Magazine 2021 17(74):360-366 Background: Colorectal cancer is one of the chief causes of death and morbidity among all types of cancer worldwide, comprising both sexes. Crocetin (CT) is a major phytoconstituent of Crocus sativus L. which performed a number of pharmacological activities. The current study established CT's anticancer effect […]
- Wiraphol Phimarn, Bunleu Sungthong, Kittisak WichaiyoPharmacognosy Magazine 2021 17(74):373-378 Background: Results from previous clinical trials in which the effects of Moringa oleifera (MO) on blood glucose and lipid profile were investigated are controversial. Objectives: The main objective of this study was to assess the effects of MO consumption on blood glucose level and lipid profile […]
- Lappaconitine hydrochloride induces apoptosis and S phase cell cycle arrest through MAPK signaling pathway in human liver cancer HepG2 cellsNa Song, Junyi Ma, Xuemei Zhang, Danni Qu, Ling Hui, Chunyan Sang, Haining LiPharmacognosy Magazine 2021 17(74):334-341 Background: Lappaconitine (LA), isolated from the root of Aconitum sinomontanum Nakai, had definite pharmacological effects, such as anticancer, analgesia, and anti-inflammation. LA and its derivatives had garnered prevalent consideration due to its analgesic and antitumor effects, but its […]
- An analytic hierarchy process multi-criteria quantitative evaluation model of cinnamon decoction piecesZi-Ye Yang, Xin-Jie Wang, Yao Zhang, Hui Gao, Hui-Nan Wang, Gui-Mei Zhang, Pei-Hua Wang, Yue-Xin Cui, Meng-Yu Chen, Zhan Chen, Ying-Zi WangPharmacognosy Magazine 2021 17(74):348-354 Background: The dried bark of Cinnamomum zeylanicum is a well-known medicinal constituent owing to its latent health benefits. The establishment of a wide-ranging and objective quality assessment method is a […]
- The gastroprotective effect of alpinia officinarum extract on indomethacin-induced topical injuries in RGM-1 Cells: Involvement of H+/K+-ATPase- and mitochondrial-mediated apoptosisLi Li, Jingwen Gong, Hailong Li, Mingyan Zhou, Yinfeng Tan, Junqing ZhangPharmacognosy Magazine 2021 17(74):256-262 Background: Topical effects are essential mechanisms of nonsteroidal anti-inflammatory drugs (NSAIDs)-induced gastric damage. Our previous study showed that the extract of Alpinia officinarum (AOE) may have some protective effects against the topical effects of indomethacin (INDO). The aim of this […]
- Resveratrol attenuates inflammation by regulating macrophage polarization via inhibition of toll-like receptor 4/MyD88 signaling pathwayYue Fan, Si-Lin Huang, Hong Li, Yu-Lin Cui, Dong-yan LiPharmacognosy Magazine 2021 17(74):321-326 Background: Resveratrol (RES) can induce macrophage polarization to achieve the immune response. Objectives: In this study, we aimed to determine whether RES attenuates inflammation by regulating macrophage polarization through inhibition of toll-like receptor 4 (TLR4)/MyD88 signaling. Materials and Methods: We measured the […]
- Ferruginol-induced apoptosis in Human Colon Cancer Cells (HCT-116) through the mitochondria-mediated apoptotic pathwayHua-Long Lin, Pei-Rui Chen, Chun-Chun Mao, Wei-E Zheng, Jia-Qi WangPharmacognosy Magazine 2021 17(74):244-249 Background: Colon cancer is the third leading cause of cancer-related deaths globally. Despite advances in systemic therapies, colorectal cancer still remains one of the foremost challenges due to high mortality rate. Objectives: In this current investigation, we observed the anticancer and proapoptotic […]
- Citral promotes the cell proliferation, differentiation, and calcium mineralization in human osteoblast-like MG-63 cellsHong Mu, Ying Pang, Lili Liu, Fengshan Li, Jianqi WangPharmacognosy Magazine 2021 17(74):250-255 Background: Osteoporosis tends to be the major consequence of fractures in women above the age of 50 years and men are prone above the age of 65 years. The structure of bone is severely deteriorated by the reduction in bone density which […]