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Recently Published Article
- Modulator effect of mangiferin on biochemical characterization in 7,12-dimethylbenz[a]anthracene-induced oral cancer in experimental hamstersMin Liu, Chengquan Wen, Shengqi PanPharmacognosy Magazine 2021 17(75):605-614 Background: Newly, chemopreventive technique might be a hopeful advancement in developing countries for treating cancers with the aid of toxic less natural-based constituents. Malignancy urges to augment effectual chemopreventive agents that are looking forward to suppressing the tumors which may be stimulated by chewing and smoking […]
- Cong Xu, Fei Liu, Yu Yang, Feng Yuan, Bo Zhou, Yadong LiuPharmacognosy Magazine 2021 17(75):623-629 Background: Osteoporosis is a serious health problem, especially in the geriatric populations. World widely, it exaggerated the 8.9 million people every year roughly. In the current analysis, we assessed the antiosteoporotic effect of fisetin on the osteoporosis model ovariectomized (OVX) […]
- Atractylodis macrocephalae rhizoma decoction and its chemically profiled subfractions alleviate the side effects of rhubarb in TCM pair medicinePei-Yuan Dou, Lian-Lian Zhu, Bin Li, Xia Liu, Makhotso Rose Lekhooa, De-Qiang Dou, Muhammad RiazPharmacognosy Magazine 2021 17(75):565-577 Background: Pair medicine is a unique feature of Chinese medicine. It refers to a specific composition of the two drugs usually used in the formulation of composite medicine, which could increase synergistically or decrease the side effects […]
- Aloperine improves renal fibrosis via regulation of toll-like receptor 4/myeloid differentiation factor 88 signaling pathwayZhen-Tian Cheng, Xiang-Ping YuanPharmacognosy Magazine 2021 17(75):587-593 Objectives: The primary goal of this study was to elucidate the effects and mechanisms of aloperine (Alo) in the renal fibrosis mice with unilateral ureteral obstruction (UUO). Materials and Methods: C57BL/6 mice were randomly separated into five groups: sham, model, Alo-L, Alo-M, and Alo-H. Serum creatinine and blood […]
- Curcumin Mediates the Proliferation and Apoptosis of Colorectal Cancer Cells by Downregulating the Expression of Interleukin-1β through the Nuclear Factor-κB Signaling PathwayXiaowu Qian, Chun Jiang, Zhengtai Zhu, Gaohua Han, Ruixing Wang, Changhe ZhangPharmacognosy Magazine 2021 17(75):539-544 Background: Colorectal cancer (CRC) is a frequently occurring malignant tumor, which is mainly observed in elderly men with no significant symptoms at the early stage. Among the malignant tumors of the digestive system, the incidence and mortality of CRC rank […]
- Rongrong Huang, Songxia LuPharmacognosy Magazine 2021 17(75):552-557 Background: The deposition of amyloid β (Aβ) proteins and hyperphosphorylation of tau proteins are the two notable features of Alzheimer's disease. During the past decades, novel drug candidates have been found from natural herbs and its derived compounds due to their broad spectra of therapeutic effects with low […]
- Deguelin treatment attenuated the lipopolysaccharides-provoked inflammation in murine macrophage and dextran sulfate sodium-inflamed acute colitis in mice through suppression of inflammatory markersFurong Wei, Xirong Lu, Xiaomin Guo, Penglin Liu, Aiting Di, Arunachalam Chinnathambi, Tahani Awad Alahmadi, Sulaiman Ali Alharbi, Lize ZhangPharmacognosy Magazine 2021 17(75):451-459 Background: Inflammatory bowel disease was a chronic inflammatory disease associated with the gastrointestinal region along with its two main types, i.e., ulcerative colitis and Crohn's disease. The occurrences of colitis were quickly […]
- In vitro genotoxicity and in vivo single-dose oral toxicity of polysaccharide fraction from the leaves of Diospyros kaki thunbChang-Won Cho, Young-Ran Song, Youn-Hwan Hwang, Young Kyoung Rhee, Won-Chul Lim, Jae Woong Choi, Kyung-Tae Lee, Hee-Do HongPharmacognosy Magazine 2021 17(75):406-412 Background: Polysaccharides isolated from medicinal herbs are regarded as important bioactive materials due to their various physiological activities. In our previous study, the polysaccharide fraction (PLE0) was separated from pectinase-digested persimmon (Diospyros kaki Thunb.) […]
- Anti-inflammatory of Alhagi sparsifolia Shap. extract: Network pharmacology analysis and experimental verificationChunliu Wang, Qiqi Liu, Zhibiao Di, Hong Zhang, Ye Li, Jun MuPharmacognosy Magazine 2021 17(75):438-444 Background: Alhagi sparsifolia Shap. (ASS) is a treasured medicinal plant and has long been employed for treating human diseases including physiological process of pain and inflammation in China. However, very tiny information has been stated about active ingredients and action […]
- Comparative assessment of α-amylase and α-glucosidase inhibition and in vitro antioxidant capacity of Garcinia schomburgkiana bark, fruit, and leaf extractsSunan Jaisamut, Boonyadist VongsakPharmacognosy Magazine 2021 17(75):445-450 Background: Garcinia schomburgkiana is a conventionally used as an herb for the treatment of diabetes, coughs, and menstrual disturbances. Objectives: The study was to examine in vitro antioxidant potentials and inhibitory effect against α-amylase and α-glucosidase of the bark, fruit, and leaf extracts of G. schomburgkiana using different […]